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Assay for early cytoplasmic effects of the src gene product of Rous sarcoma virus

When microinjected into normal fibroblasts, cytoplasmic extracts of cells transformed by Rous sarcoma virus caused dissolution of microfilament bundles. This activity was not found in extracts of normal cells. The maximum effect was seen within 30 min of injection, and the activity could still be me...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: McClain, Donald A., Maness, Patricia F., Edelman, Gerald M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1978
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392641/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/208075/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.6.2750
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