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Inhibition of translation by poliovirus: inactivation of a specific initiation factor.

Translation of vesicular stomatitis virus (VSV) mRNA, like host mRNA translation, is inhibited in cells infected with poliovirus. To study the mechanism of poliovirus-induced inhibition of protein synthesis, we prepared extracts from poliovirus-infected and uninfected HeLa cells. Poliovirus mRNA was...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Rose, J K, Trachsel, H, Leong, K, Baltimore, D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1978
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392637/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/208073/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.6.2732
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