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First-line natalizumab in multiple sclerosis: rationale, patient selection, benefits and risks

Natalizumab (NTZ) is a highly effective disease modifying therapy for the treatment of relapsing forms of multiple sclerosis (MS). Despite evidence to support its use as first-line therapy, risk of NTZ-associated progressive multifocal leukoencephalopathy (PML) has largely contributed to it being re...

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Autori principali: Nicholas, Jacqueline Ann, Racke, Michael Karl, Imitola, Jamie, Boster, Aaron Lee
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926344/
https://ncbi.nlm.nih.gov/pubmed/24587891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040622313514790
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