Targeted disruption of the mZP3 gene results in production of eggs lacking a zona pellucida and infertility in female mice.

Mammalian eggs are surrounded by a thick extracellular coat, the zona pellucida, that plays important roles during early development. The mouse egg zona pellucida is constructed of three glycoproteins, called mZP1, mZP2, and mZP3. The gene encoding mZP3 is expressed only by growing oocytes during a...

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Main Authors: Liu, C, Litscher, E S, Mortillo, S, Sakai, Y, Kinloch, R A, Stewart, C L, Wassarman, P M
格式: Artigo
語言:Inglês
出版: 1996
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC39263/
https://ncbi.nlm.nih.gov/pubmed/8643592
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