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Purification of the tetrodotoxin-binding component associated with the voltage-sensitive sodium channel from Electrophorus electricus electroplax membranes.

The tetrodotoxin-binding component associated with the voltage-sensitive sodium channel from electroplax membranes of Electrophorus electricus has been purified. The toxin-binding site could be efficiently solubilized with Lubrol-PX, resulting in an extract of high initial specific activity. Purific...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Agnew, W S, Levinson, S R, Brabson, J S, Raftery, M A
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1978
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392611/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/275831/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.6.2606
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