Phase I Study of Dose Escalation in Hypofractionated Proton Beam Therapy for Thoracic Malignancies

Twenty five patients were treated with proton beam therapy to 45 Gy(RBE), 52.5 Gy(RBE), or 60 Gy(RBE) in 15 fractions using a 3+3 study design. Dose constraints were based on biologically equivalent doses to standard fractionated treatment. Two patients experienced high-grade toxicity, both possibly...

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Detalhes bibliográficos
Main Authors: Gomez, Daniel R., Gillin, Michael, Liao, Zhongxing, Wei, Caimiao, Lin, Steven H., Swanick, Cameron, Alvarado, Tina, Komaki, Ritsuko, Cox, James D., Chang, Joe Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926094/
https://ncbi.nlm.nih.gov/pubmed/23688815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2013.03.035
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