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Coarse-grained simulations of the gating current in the voltage-activated Kv1.2 channel

Quantitative structure-based modeling of voltage activation of ion channels is very challenging. For example, it is very hard to reach converging results, by microscopic simulations while macroscopic treatments involve major uncertainties regarding key features. The current work overcomes some of th...

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Detalhes bibliográficos
Main Authors: Kim, Ilsoo, Warshel, Arieh
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926088/
https://ncbi.nlm.nih.gov/pubmed/24464485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1324014111
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