Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal

One of the main impediments for obtaining DNA sequences from ancient human skeletons is the presence of contaminating modern human DNA molecules in many fossil samples and laboratory reagents. However, DNA fragments isolated from ancient specimens show a characteristic DNA damage pattern caused by m...

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Библиографические подробности
Главные авторы: Skoglund, Pontus, Northoff, Bernd H., Shunkov, Michael V., Derevianko, Anatoli P., Pääbo, Svante, Krause, Johannes, Jakobsson, Mattias
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2014
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926038/
https://ncbi.nlm.nih.gov/pubmed/24469802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318934111
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