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Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal

One of the main impediments for obtaining DNA sequences from ancient human skeletons is the presence of contaminating modern human DNA molecules in many fossil samples and laboratory reagents. However, DNA fragments isolated from ancient specimens show a characteristic DNA damage pattern caused by m...

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Detalhes bibliográficos
Main Authors: Skoglund, Pontus, Northoff, Bernd H., Shunkov, Michael V., Derevianko, Anatoli P., Pääbo, Svante, Krause, Johannes, Jakobsson, Mattias
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926038/
https://ncbi.nlm.nih.gov/pubmed/24469802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318934111
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