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Lactate-mediated glia-neuronal signalling in the mammalian brain

Astrocytes produce and release L-lactate as a potential source of energy for neurons. Here we present evidence that L-lactate, independently of its caloric value, serves as an astrocytic signalling molecule in the locus coeruleus (LC). The LC is the principal source of norepinephrine to the frontal...

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Bibliografiske detaljer
Main Authors: Tang, F., Lane, S., Korsak, A., Paton, J. F. R., Gourine, A. V., Kasparov, S., Teschemacher, A. G.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3926012/
https://ncbi.nlm.nih.gov/pubmed/24518663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4284
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