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Genome sequencing and analysis of the paclitaxel-producing endophytic fungus Penicillium aurantiogriseum NRRL 62431

BACKGROUND: Paclitaxel (Taxol™) is an important anticancer drug with a unique mode of action. The biosynthesis of paclitaxel had been considered restricted to the Taxus species until it was discovered in Taxomyces andreanae, an endophytic fungus of T. brevifolia. Subsequently, paclitaxel was found i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yang, Yanfang, Zhao, Hainan, Barrero, Roberto A, Zhang, Baohong, Sun, Guiling, Wilson, Iain W, Xie, Fuliang, Walker, Kevin D, Parks, Joshua W, Bruce, Robert, Guo, Guangwu, Chen, Li, Zhang, Yong, Huang, Xin, Tang, Qi, Liu, Hongwei, Bellgard, Matthew I, Qiu, Deyou, Lai, Jinsheng, Hoffman, Angela
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925984/
https://ncbi.nlm.nih.gov/pubmed/24460898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-69
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