Molecular characterization of de novo Ph+ Acute Myeloid Leukemia

Philadelphia chromosome-positive (Ph+) AML is a controversial diagnosis, as others propose it represents CML in blast phase (CML-BP). NPM1 mutations occur in 25-35% of AML but are absent in CML patients. Conversely, ABL1 mutations occur in 25% of Imatinib-naïve CML-BP but are not described in AML pa...

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Detalhes bibliográficos
Main Authors: Konoplev, Sergej, Yin, C. Cameron, Kornblau, Steven M., Kantarjian, Hagop M., Konopleva, Marina, Andreeff, Michael, Lu, Gary, Zuo, Zhuang, Luthra, Rajyalakshmi, Medeiros, L. Jeffrey, Bueso-Ramos, Carlos E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925981/
https://ncbi.nlm.nih.gov/pubmed/22691121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2012.701739
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