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Targeting Six1 by lentivirus-mediated RNA interference inhibits colorectal cancer cell growth and invasion

The Six1 homeodomain protein is a developmental transcription factor that has been implicated in tumor onset and progression. Recently, it’s reported that overexpression of Six1 is sufficient to induce epithelial-to-mesenchymal transition (EMT) and metastasis of colorectal cancer. Moreover, its expr...

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Detalhes bibliográficos
Main Authors: Li, Zhaoming, Tian, Tian, Hu, Xiaopeng, Zhang, Xudong, Li, Lifeng, Nan, Feifei, Chang, Yu, Wang, Xinhua, Sun, Zhenchang, Lv, Feng, Zhang, Mingzhi
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925907/
https://ncbi.nlm.nih.gov/pubmed/24551283
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