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Molecular mechanisms of template-independent RNA polymerization by tRNA nucleotidyltransferases

The universal 3′-terminal CCA sequence of tRNA is built and/or synthesized by the CCA-adding enzyme, CTP:(ATP) tRNA nucleotidyltransferase. This RNA polymerase has no nucleic acid template, but faithfully synthesizes the defined CCA sequence on the 3′-terminus of tRNA at one time, using CTP and ATP...

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Autors principals: Tomita, Kozo, Yamashita, Seisuke
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925840/
https://ncbi.nlm.nih.gov/pubmed/24596576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00036
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