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High Molecular Weight Complex Analysis of Epstein-Barr Virus Latent Membrane Protein 1 (LMP-1): Structural Insights into LMP-1’s Homo-Oligomerization and Lipid Raft Association

LMP-1 is a constitutively active Tumor Necrosis Factor Receptor analog encoded by Epstein-Barr virus. LMP-1 activation correlates with oligomerization and raft localization, but direct evidence of LMP-1 oligomers is limited. We report that LMP-1 forms multiple high molecular weight native LMP-1 comp...

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Detalhes bibliográficos
Main Authors: Wrobel, Christopher M., Geiger, Timothy R., Nix, Rebecca N., Robitaille, Aaron M., Balser, Sandra, Cervantes, Alfredo, Gonzalez, Miguel, Martin, Jennifer M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925771/
https://ncbi.nlm.nih.gov/pubmed/24075898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2013.09.025
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