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Src and CXCR4 are involved in the invasiveness of breast cancer cells with acquired resistance to lapatinib
Lapatinib is a dual EGFR and ErbB-2 tyrosine kinase inhibitor that has significantly improved the clinical outcome of ErbB-2-overexpressing breast cancer patients. However, patients inexorably develop mechanisms of resistance that limit the efficacy of the drug. In order to identify potential target...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3925726/ https://ncbi.nlm.nih.gov/pubmed/24200972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26899 |
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