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Variable region genes for the immunoglobulin framework are assembled from small segments of DNA—A hypothesis

Sequences of each of the four framework segments FR1, FR2, FR3, and FR4 of the variable regions (V-regions) of light and heavy chains of immunoglobulins were grouped into sets with identical sequences. Sets contained from 1 to 18 members. When each V-region was traced from one FR to the next, it was...

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Bibliografische gegevens
Hoofdauteurs: Kabat, Elvin A., Wu, Tai Te, Bilofsky, Howard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1978
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC392567/
https://ncbi.nlm.nih.gov/pubmed/97670
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