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Promoter Methylation of SFRP3 Is Frequent in Hepatocellular Carcinoma

Oncogenic activation of the Wnt/β-catenin signaling pathway is common in human cancers. The secreted frizzled-related proteins (SFRPs) function as negative regulators of Wnt signaling and have important implications in carcinogenesis. Because there have been no reports about the role of SFRP3 in hep...

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Detalhes bibliográficos
Principais autores: Lin, Ya-Wen, Shih, Yu-Lueng, Lien, Gi-Shih, Suk, Fat-Moon, Hsieh, Chung-Bao, Yan, Ming-De
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925610/
https://ncbi.nlm.nih.gov/pubmed/24591760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/351863
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