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CDK/CCN and CDKI Alterations for Cancer Prognosis and Therapeutic Predictivity

The regulation of cell growth and division occurs in an accurate sequential manner. It is dictated by the accumulation of cyclins (CCNs) and cyclin-dependent kinases (CDKs) complexes and degradation of CCNs. In human tumors, instead, the cell cycle is deregulated, causing absence of differentiation...

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Detalhes bibliográficos
Main Authors: Bonelli, Patrizia, Tuccillo, Franca Maria, Borrelli, Antonella, Schiattarella, Antonietta, Buonaguro, Franco Maria
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925518/
https://ncbi.nlm.nih.gov/pubmed/24605326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/361020
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