Survivin-responsive conditionally replicating adenovirus kills rhabdomyosarcoma stem cells more efficiently than their progeny

BACKGROUND: Effective methods for eradicating cancer stem cells (CSCs), which are highly tumorigenic and resistant to conventional therapies, are urgently needed. Our previous studies demonstrated that survivin-responsive conditionally replicating adenoviruses regulated with multiple factors (Surv.m...

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Autors principals: Tanoue, Kiyonori, Wang, Yuqing, Ikeda, Minako, Mitsui, Kaoru, Irie, Rie, Setoguchi, Takao, Komiya, Setsuro, Natsugoe, Shoji, Kosai, Ken-ichiro
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925355/
https://ncbi.nlm.nih.gov/pubmed/24467821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-27
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