Lipid overloading during liver regeneration causes delayed hepatocyte DNA replication by increasing ER stress in mice with simple hepatic steatosis

BACKGROUND AND AIM: Impaired fatty liver regeneration has already been reported in many genetic modification models. However, in diet-induced simple hepatic steatosis, which showed similar phenotype with clinical pathology, whether liver regeneration is impaired or not remains unclear. In this study...

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Détails bibliographiques
Auteurs principaux: Hamano, Mina, Ezaki, Hisao, Kiso, Shinichi, Furuta, Kunimaro, Egawa, Mayumi, Kizu, Takashi, Chatani, Norihiro, Kamada, Yoshihiro, Yoshida, Yuichi, Takehara, Tetsuo
Format: Artigo
Langue:Inglês
Publié: Springer Japan 2013
Sujets:
Original Article—Liver, Pancreas, and Biliary Tract
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925298/
https://ncbi.nlm.nih.gov/pubmed/23512345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00535-013-0780-7
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