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Visual–spatial learning impairments are associated with hippocampal PSD-95 protein dysregulation in a mouse model of fragile X syndrome

Fragile X syndrome is the most common cause of inherited intellectual disability and is caused by the lack of fragile X mental retardation protein (FMRP) expression. In-vitro findings in mice and post-mortem autopsies in humans are characterized by dendritic spine abnormalities in the absence of Fmr...

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Detalhes bibliográficos
Main Authors: Gandhi, Réno M., Kogan, Cary S., Messier, Claude, MacLeod, Lindsey S.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925173/
https://ncbi.nlm.nih.gov/pubmed/24323121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000000087
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