Mesenchymal Stromal Cells Mediate Aspergillus Hyphal Extract-Induced Allergic Airway Inflammation by Inhibition of the Th17 Signaling Pathway

Systemic administration of mesenchymal stromal cells (MSCs) suppresses airway inflammation and methacholine-induced airway hyper-responsiveness (AHR) in mouse models of T helper cell (Th) type 2-mediated eosinophilic allergic airway inflammation (AAI); however, the efficacy of MSCs in mouse models o...

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Auteurs principaux: Lathrop, Melissa J., Brooks, Elice M., Bonenfant, Nick R., Sokocevic, Dino, Borg, Zachary D., Goodwin, Meagan, Loi, Roberto, Cruz, Fernanda, Dunaway, Chad W., Steele, Chad, Weiss, Daniel J.
Format: Artigo
Langue:Inglês
Publié: AlphaMed Press 2014
Sujets:
Cell-Based Drug Development, Screening, and Toxicology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925050/
https://ncbi.nlm.nih.gov/pubmed/24436442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2013-0061
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