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ADN-1184 a monoaminergic ligand with 5-HT(6/7) receptor antagonist activity: pharmacological profile and potential therapeutic utility

BACKGROUND AND PURPOSE: Many dementia patients exhibit behavioural and psychological symptoms (BPSD) that include psychosis, aggressivity, depression and anxiety. Antipsychotic drugs are frequently prescribed but fail to significantly attenuate mood deficits, may interfere with cognitive function an...

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Autors principals: Kołaczkowski, M, Mierzejewski, P, Bieńkowski, P, Wesołowska, A, Newman-Tancredi, A
Format: Artigo
Idioma:Inglês
Publicat: John wiley & Sons Ltd 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925036/
https://ncbi.nlm.nih.gov/pubmed/24199650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12509
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