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Constitutive activation of STAT5A and STAT5B regulates IgM secretion in Waldenström's macroglobulinemia

Activation of the Janus kinase family/signal transducer and activator of transcription (JAK/STAT) signaling pathway has been associated with the pathogenesis and progression of both solid and hematologic malignancies. We have detected constitutive activation of STAT5 in malignant B cells derived fro...

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Библиографические подробности
Главные авторы: Hodge, Lucy S., Ziesmer, Steven C., Yang, Zhi-Zhang, Secreto, Frank J., Novak, Anne J., Ansell, Stephen M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924927/
https://ncbi.nlm.nih.gov/pubmed/24335105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-08-521963
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