Epigenetic Regulation of the Apolipoprotein Gene Cluster by a Long Non-Protein-Coding RNA

Apolipoprotein A-1 (APOA1) is the major protein component of high-density lipoprotein (HDL) in plasma. We have identified an endogenously expressed long non-coding natural antisense transcript, APOA1-AS, which acts as a negative transcriptional regulator of APOA1, both in vitro and in vivo. Inhibiti...

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Bibliografiske detaljer
Main Authors: Halley, Paul, Kadakkuzha, Beena M., Faghihi, Mohammad Ali, Magistri, Marco, Zeier, Zane, Khorkova, Olga, Coito, Carlos, Hsiao, Jane, Lawrence, Matthew, Wahlestedt, Claes
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924898/
https://ncbi.nlm.nih.gov/pubmed/24388749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.12.015
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