Chargement en cours...

Estradiol-17β and its CYP450s- and COMT–Derived Metabolites Selectively Stimulate Production of Prostacyclin in Uterine Artery Endothelial Cells: Role of ER-α Versus ER-β

Metabolism of estradiol-17β to 2-hydroxyestradiol, 4-hydroxyestradiol, 2-methoxyestradiol and 4-methoxyestradiol, contributes importantly to the vascular effects of estradiol-17β in several vascular beds. However, little is known about the role of estradiol-17β metabolites via the different estrogen...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jobe, Sheikh O, Ramadoss, Jayanth, Wargin, Andrew J, Magness, Ronald R
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924857/
https://ncbi.nlm.nih.gov/pubmed/23319543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.200717
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!