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Mechanotransduction in the Endothelium: Role of Membrane Proteins and Reactive Oxygen Species in Sensing, Transduction, and Transmission of the Signal with Altered Blood Flow

Significance: Changes in shear stress associated with alterations in blood flow initiate a signaling cascade that modulates the vascular phenotype. Shear stress is “sensed” by the endothelium via a mechanosensitive complex on the endothelial cell (EC) membrane that has been characterized as a “mecha...

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Detalhes bibliográficos
Main Authors: Chatterjee, Shampa, Fisher, Aron B.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924805/
https://ncbi.nlm.nih.gov/pubmed/24328670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2013.5624
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