Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications

Methods for rapid surface immobilization of bioactive small molecules with control over orientation and immobilization density are highly desirable for biosensor and microarray applications. In this Study, we use a highly efficient covalent bioorthogonal [4+2] cycloaddition reaction between trans-cy...

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Detalhes bibliográficos
Main Authors: Tassa, Carlos, Liong, Monty, Hilderbrand, Scott, Sandler, Jason E., Reiner, Thomas, Keliher, Edmund J., Weissleder, Ralph, Shaw, Stanley Y.
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2013
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924759/
https://ncbi.nlm.nih.gov/pubmed/24084440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50772
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