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Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications

Methods for rapid surface immobilization of bioactive small molecules with control over orientation and immobilization density are highly desirable for biosensor and microarray applications. In this Study, we use a highly efficient covalent bioorthogonal [4+2] cycloaddition reaction between trans-cy...

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Sonraí Bibleagrafaíochta
Main Authors: Tassa, Carlos, Liong, Monty, Hilderbrand, Scott, Sandler, Jason E., Reiner, Thomas, Keliher, Edmund J., Weissleder, Ralph, Shaw, Stanley Y.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MyJove Corporation 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924759/
https://ncbi.nlm.nih.gov/pubmed/24084440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50772
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