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A Convenient Approach to Synthesizing Peptide C-Terminal N-Alkyl Amides

Peptide C-terminal N-alkyl amides have gained more attention over the past decade due to their biological properties, including improved pharmacokinetic and pharmacodynamic profiles. However, the synthesis of this type of peptide on solid phase by current available methods can be challenging. Here w...

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Autors principals: Fang, Wei-Jie, Yakovleva, Tatyana, Aldrich, Jane V.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924563/
https://ncbi.nlm.nih.gov/pubmed/22252422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.21600
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