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Differential desensitization of functional adrenergic receptors in normal and malignant myeloid cells: Relationship to receptor-mediated hormone cytotoxicity

Malignant myeloid leukemic cells and normal macrophages and granulocytes have functional β-adrenergic receptors, which have been quantitated by radioreceptor binding with the β-adrenergic antagonist [(3)H]dihydroalprenolol and by induction of cyclic AMP by adrenergic hormones. Both the normal and le...

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Detalhes bibliográficos
Main Authors: Simantov, Rabi, Sachs, Leo
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC392429/
https://ncbi.nlm.nih.gov/pubmed/25440
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