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Evolution of Mammalian Opn5 as a Specialized UV-absorbing Pigment by a Single Amino Acid Mutation

Opn5 is one of the recently identified opsin groups that is responsible for nonvisual photoreception in animals. We previously showed that a chicken homolog of mammalian Opn5 (Opn5m) is a G(i)-coupled UV sensor having molecular properties typical of bistable pigments. Here we demonstrated that mamma...

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Bibliografiska uppgifter
Huvudupphovsmän: Yamashita, Takahiro, Ono, Katsuhiko, Ohuchi, Hideyo, Yumoto, Akane, Gotoh, Hitoshi, Tomonari, Sayuri, Sakai, Kazumi, Fujita, Hirofumi, Imamoto, Yasushi, Noji, Sumihare, Nakamura, Katsuki, Shichida, Yoshinori
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924266/
https://ncbi.nlm.nih.gov/pubmed/24403072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.514075
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