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Sample size calculation based on exact test for assessing differential expression analysis in RNA-seq data

BACKGROUND: Sample size calculation is an important issue in the experimental design of biomedical research. For RNA-seq experiments, the sample size calculation method based on the Poisson model has been proposed; however, when there are biological replicates, RNA-seq data could exhibit variation s...

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Detalhes bibliográficos
Main Authors: Li, Chung-I, Su, Pei-Fang, Shyr, Yu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924199/
https://ncbi.nlm.nih.gov/pubmed/24314022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-357
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