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Preparation and template activities of polynucleotides containing O2- and O4-alkyluridine.

O2-Ethyl-UDP and O4-methyl-UDP have been prepared and copolymerized in various proportions with UDP or CDP, using polynucleotide phosphorylase. The copolymers were used as templates for DNA-dependent RNA polymerases in the presence of Mn2+. Both of the O-alkylated uridines caused a similar misincorp...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Singer, B, Fraenkel-Conrat, H, Kuśmierek, J T
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1978
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392411/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/273902/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.4.1722
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