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Preparation and template activities of polynucleotides containing O2- and O4-alkyluridine.

O2-Ethyl-UDP and O4-methyl-UDP have been prepared and copolymerized in various proportions with UDP or CDP, using polynucleotide phosphorylase. The copolymers were used as templates for DNA-dependent RNA polymerases in the presence of Mn2+. Both of the O-alkylated uridines caused a similar misincorp...

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Autores principales: Singer, B, Fraenkel-Conrat, H, Kuśmierek, J T
Formato: Artigo
Lenguaje:Inglês
Publicado: 1978
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC392411/
https://ncbi.nlm.nih.gov/pubmed/273902
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