Late Multiple Organ Surge in Interferon-Regulated Target Genes Characterizes Staphylococcal Enterotoxin B Lethality

BACKGROUND: Bacterial superantigens are virulence factors that cause toxic shock syndrome. Here, the genome-wide, temporal response of mice to lethal intranasal staphylococcal enterotoxin B (SEB) challenge was investigated in six tissues. RESULTS: The earliest responses and largest number of affecte...

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Main Authors: Ferreyra, Gabriela A., Elinoff, Jason M., Demirkale, Cumhur Y., Starost, Matthew F., Buckley, Marilyn, Munson, Peter J., Krakauer, Teresa, Danner, Robert L.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923834/
https://ncbi.nlm.nih.gov/pubmed/24551153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088756
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