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Rapamycin Protects Mice from Staphylococcal Enterotoxin B-Induced Toxic Shock and Blocks Cytokine Release In Vitro and In Vivo

Staphylococcal enterotoxins are potent activators for human T cells and cause lethal toxic shock. Rapamycin, an immunosuppressant, was tested for its ability to inhibit staphylococcal enterotoxin B (SEB)-induced activation of human peripheral blood mononuclear cells (PBMC) in vitro and toxin-mediate...

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Hlavní autoři: Krakauer, Teresa, Buckley, Marilyn, Issaq, Haleem J., Fox, Stephen D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825991/
https://ncbi.nlm.nih.gov/pubmed/20086156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01015-09
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