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Constructing the Energy Landscape for Genetic Switching System Driven by Intrinsic Noise

Genetic switching driven by noise is a fundamental cellular process in genetic regulatory networks. Quantitatively characterizing this switching and its fluctuation properties is a key problem in computational biology. With an autoregulatory dimer model as a specific example, we design a general met...

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Autors principals: Lv, Cheng, Li, Xiaoguang, Li, Fangting, Li, Tiejun
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923795/
https://ncbi.nlm.nih.gov/pubmed/24551081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088167
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