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High-affinity peptide-based anticancer vaccination to overcome resistance to immunostimulatory antibodies

We tested how to eradicate long-established immunogenic tumors that were resistant to the monoclonal antibody-mediated blockade of PD-L1 (PD-1 ligand 1) and cytotoxic T lymphocyte-associated protein 4 (CTLA4). Bacterial vaccination with a tumor-specific peptide exhibiting a high affinity for its res...

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Hlavní autoři: Binder, David C, Schreiber, Hans
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923789/
https://ncbi.nlm.nih.gov/pubmed/24563823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.26704
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