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Opposing effects of dopaminergic to cholinergic compounds on a cerebral dopamine-activated adenylate cyclase.

In contrast to antipsychosis drugs which inhibit the dopamine-activated adenylate cyclase [ATP pyrophosphate-lyase (cyclizing), EC 4.6.1.1] of caudate nucleus, dopaminergic drugs for treatment of Parkinson's disease stimulate this cyclase. Stimulants and inhibitors of cholinergic neurons inhibited t...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Tang, L C, Cotzias, G C
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1977
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392375/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/265541/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.2.769
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