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Lymphocyte mitogenesis induced by a mammalian liver protein that specifically binds desialylated glycoproteins.

A purified rabbit liver membrane protein that binds desialylated glycoproteins has been shown to be a mitogen for human peripheral lymphocytes. The mitogenic activity is specific for desialylated thymus-derived (T)-cells. The loss of mitogenicity upon exposure of the binding protein to neuraminidase...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Novogrodsky, A, Ashwell, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1977
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392355/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/265530/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.2.676
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