Naturally Acquired Antibodies Specific for Plasmodium falciparum Reticulocyte-Binding Protein Homologue 5 Inhibit Parasite Growth and Predict Protection From Malaria

Background. Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) is a blood-stage parasite protein essential for host erythrocyte invasion. PfRH5-specific antibodies raised in animals inhibit parasite growth in vitro, but the relevance of naturally acquired PfRH5-specific antibodie...

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Main Authors: Tran, Tuan M., Ongoiba, Aissata, Coursen, Jill, Crosnier, Cecile, Diouf, Ababacar, Huang, Chiung-Yu, Li, Shanping, Doumbo, Safiatou, Doumtabe, Didier, Kone, Younoussou, Bathily, Aboudramane, Dia, Seydou, Niangaly, Moussa, Dara, Charles, Sangala, Jules, Miller, Louis H., Doumbo, Ogobara K., Kayentao, Kassoum, Long, Carole A., Miura, Kazutoyo, Wright, Gavin J., Traore, Boubacar, Crompton, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923542/
https://ncbi.nlm.nih.gov/pubmed/24133188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit553
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