UTILIZATION OF AN EMR-BIOREPOSITORY TO IDENTIFY THE GENETIC PREDICTORS OF CALCINEURIN-INHIBITOR TOXICITY IN HEART TRANSPLANT RECIPIENTS

Calcineurin-inhibitors CI are immunosuppressive agents prescribed to patients after solid organ transplant to prevent rejection. Although these drugs have been transformative for allograft survival, long-term use is complicated by side effects including nephrotoxicity. Given the narrow therapeutic i...

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Hlavní autoři: Oetjens, Matthew, Bush, William S., Birdwell, Kelly A., Dilks, Holli H., Bowton, Erica A., Denny, Joshua C., Wilke, Russell A., Roden, Dan M., Crawford, Dana C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923429/
https://ncbi.nlm.nih.gov/pubmed/24297552
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