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Distinct enzyme combinations in AKAP signalling complexes permit functional diversity

Specificity in cell signalling can be influenced by the targeting of different enzyme combinations to substrates. The A-kinase anchoring protein AKAP79/150 is a multivalent scaffolding protein that coordinates the subcellular localization of second-messenger-regulated enzymes, such as protein kinase...

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Hlavní autoři: Hoshi, Naoto, Langeberg, Lorene K., Scott, John D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923410/
https://ncbi.nlm.nih.gov/pubmed/16228013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1315
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