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Human TP53 polymorphism (rs1042522) modelled in mouse does not affect glucose metabolism and body composition

Variation in TP53 has been associated with cancer. The pro-allele of a TP53 polymorphism in codon 72 (rs1042522) has been associated with longevity. Recently, we showed that the same allele might be involved in preservation of glucose metabolism, body composition and blood pressure during ageing. He...

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Detalhes bibliográficos
Main Authors: Reiling, Erwin, Speksnijder, Ewoud N., Pronk, Amanda C. M., van den Berg, Sjoerd A. A., Neggers, Silvia J. W., Rietbroek, Ilma, van Steeg, Harry, Dollé, Martijn E. T.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923217/
https://ncbi.nlm.nih.gov/pubmed/24522546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04091
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