A monomeric form of pyruvate kinase in human pyruvate kinase deficiency.
A mutant pyruvate kinase (ATP:pyruvate 2-O-phosphotransferase, EC 2.7.1.40) from human erythrocytes which is easily separated into monomers and dimers by gel chromatography is described. Tht mutant enzyme shows almost the same pH optimum and thermostability as normal enzyme, but has a decreased stab...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1977
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC392317/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15247/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.2.501 |
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