A lentiviral sponge for miR-101 regulates RanBP9 expression and amyloid precursor protein metabolism in hippocampal neurons

Neurodegeneration associated with amyloid β (Aβ) peptide accumulation, synaptic loss, and memory impairment are pathophysiological features of Alzheimer's disease (AD). Numerous microRNAs regulate amyloid precursor protein (APP) expression and metabolism. We previously reported that miR-101 is...

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Main Authors: Barbato, Christian, Pezzola, Silvia, Caggiano, Cinzia, Antonelli, Martina, Frisone, Paola, Ciotti, Maria Teresa, Ruberti, Francesca
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2014
主題:
Neuroscience
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923151/
https://ncbi.nlm.nih.gov/pubmed/24592211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00037
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