Toll like receptor (TLR)-4 as a regulator of peripheral endogenous opioid-mediated analgesia in inflammation

BACKGROUND: Leukocytes containing opioid peptides locally control inflammatory pain. In the early phase of complete Freund’s adjuvant (CFA)-induced hind paw inflammation, formyl peptides (derived e.g. from Mycobacterium butyricum) trigger the release of opioid peptides from neutrophils contributing...

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Autores principales: Sauer, Reine-Solange, Hackel, Dagmar, Morschel, Laura, Sahlbach, Henrike, Wang, Ying, Mousa, Shaaban A, Roewer, Norbert, Brack, Alexander, Rittner, Heike L
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922964/
https://ncbi.nlm.nih.gov/pubmed/24499354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-10-10
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