CMV Latent Infection Improves CD8+ T Response to SEB Due to Expansion of Polyfunctional CD57+ Cells in Young Individuals

Cytomegalovirus (CMV) latent infection has a deleterious effect on the efficacy of influenza vaccination in the elderly, suggesting that CMV restricts immunological diversity impairing the immune system functionality in old age. Polyfunctional T cells produce multiple cytokines and higher amounts th...

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Autors principals: Pera, Alejandra, Campos, Carmen, Corona, Alonso, Sanchez-Correa, Beatriz, Tarazona, Raquel, Larbi, Anis, Solana, Rafael
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922920/
https://ncbi.nlm.nih.gov/pubmed/24533103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088538
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