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Analysis of early phase and subsequent phase III stroke studies of neuroprotectants: outcomes and predictors for success

BACKGROUND: Efficacy of neuroprotective treatments for ischemic stroke was not convincingly demonstrated in clinical phase III trials so far, whereas some preceding early phase studies found neuroprotection to be beneficial. We aimed to determine the frequency with which phase III studies are preced...

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Main Authors: Minnerup, Jens, Wersching, Heike, Schilling, Matthias, Schäbitz, Wolf Rüdiger
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922860/
https://ncbi.nlm.nih.gov/pubmed/24502346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-7378-6-2
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