Changes in the pharmacokinetic of sildenafil citrate in rats with Streptozotocin-induced diabetic nephropathy

AIM: The present investigates deals with the change in the pharmacokinetic of Sildenafil citrate (SIL) in disease condition like diabetic nephropathy (DN). METHOD: Diabetes was induced in rats by administering Streptozotocin i.e. STZ (60 mg/kg, IP) saline solution. Assessment of diabetes was done by...

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Main Authors: Tripathi, Alok S, Mazumder, Papiya M, Chandewar, Anil V
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922855/
https://ncbi.nlm.nih.gov/pubmed/24398037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2251-6581-13-8
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