Ceftriaxone upregulates the glutamate transporter in medial prefrontal cortex and blocks reinstatement of methamphetamine seeking in a condition place preference paradigm

Glutamate signaling plays an essential role in drug-seeking behavior. Using reinstatement of conditioned place preference (CPP), we determined whether ceftriaxone, a β-lactam antibiotic known to increase the expression and activity of the glutamate transporter (EAAT(2)) on glial cells, blocks metham...

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Autori principali: Abulseoud, Osama A., Miller, Joseph D., Wu, Jinhua, Choi, Doo-Sup, Holschneider, Daniel P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922613/
https://ncbi.nlm.nih.gov/pubmed/22521042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.03.045
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